Best Defense Against Omicron, Delta? Get Boosted

Rush infectious disease specialist urges vaccinations to combat COVID-19 variants
Omicron

On Dec. 1, the first U.S. case of the new COVID-19 variant, omicron, was detected in northern California, less than a week after the World Health Organization deemed it a 鈥.鈥 The infected individual was fully vaccinated and had just returned from South Africa, where omicron was first detected.

, an infectious disease specialist and associate professor at 脱衣直播, expects that Chicago won鈥檛 be spared from the omicron variant.

鈥淕iven how it has spread across the world, we will likely see it coming to our region at some point,鈥 Lin says. 鈥淏ut the question will be how it competes with the delta variant, which continues to be the dominant variant worldwide, and if it will cause a new wave of infection. That is impossible to predict at this point.鈥

So what can people do to protect themselves against both omicron and delta?

Lin encourages everyone age 5 and older to get vaccinated against COVID-19. He also urges all adults to get their COVID-19 boosters as recommended by the Centers for Disease Control and Prevention. 鈥淭his will increase the likelihood that the vaccine will provide at least partial immunity,鈥 Lin says.

Mutations may cause the virus to spread faster

How fast omicron could spread through the Chicago area is unclear, but Lin is concerned that omicron鈥檚 large number of genetic mutations might give the new COVID-19 variant an edge over earlier strains.

鈥淰iruses evolve through mutations,鈥 Lin says, adding that such mutations could cause omicron to spread more quickly than previous variants. 鈥淭he omicron variant seems to have outpaced the delta variant in parts of South Africa. So, there鈥檚 cause for concern that it may exhibit more efficient transmission properties.鈥

Vaccines may not be as effective but will still offer protection

Another concern is that current COVID-19 vaccines may not work as well against the new variant. 鈥淭here are a large number of mutations on the omicron variant鈥檚 spike protein, which is the target of vaccines and the antibodies we make,鈥 Lin says. 鈥淪o, if that spike protein changes substantially, then the antibodies we have as a result of the vaccine or natural immunity may not be as effective.鈥

However, Lin is encouraged by the fact that current COVID-19 vaccines offer protection through two different means. One way is by training our immune systems to develop antibodies that target the virus. The other is through cell-mediated immunity, in which the vaccine teaches our bodies to fight the virus even without the ideal antibodies, he says.

In a matter of weeks, Lin expects scientists will have more information on the how well existing vaccines work against omicron by testing the blood in vaccinated people who鈥檝e been infected with the new strain. What will likely take longer is determining if omicron can cause more severe COVID-19, as some scientists have speculated, although the evidence is limited so far. 鈥淲e just don鈥檛 know until we have more clinical and epidemiologic data,鈥 Lin says.

Even as the U.S. implements more travel restrictions, Lin does not believe the emergence of omicron will lead to more lockdowns here at home. He is also optimistic that the months ahead will not be as difficult as the first months of the pandemic, thanks to the vaccines. 鈥淢y guess is that we鈥檙e beyond the worst of the pandemic, and that includes the lockdowns,鈥 he says. 鈥淚 believe that the vaccines, although they will be imperfect, will still provide some measure of protection.鈥

Delta remains key concern

Lin says the delta variant remains the immediate concern for Chicago and the rest of Illinois.

鈥淲e鈥檝e seen an increase in COVID-19 cases over the past month or so, which has been driven by delta,鈥 Lin says. He attributes the rise in cases to human behavior like less vigilant masking and relaxed social distancing combined with the millions of Illinois residents who are still unvaccinated.

Lin also reminds Chicago-area residents that they have a lot of control over what happens in their community and beyond in the coming months. 鈥淚t鈥檚 not just up to the virus. It鈥檚 really up to us and what we do for basic prevention,鈥 he says. 鈥淕etting vaccinated, wearing a face mask, practicing hand hygiene and social distancing when possible all are key prevention steps that have not changed since the early parts of the pandemic.鈥

If you have not yet received a COVID-19 vaccine or would like to get a booster, you can schedule an appointment to receive one now at our vaccine clinics.

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